SELPHYL^®
PRFM

SELPHYL® Platelet-Rich Fibrin Matrix (PRFM)

SELPHYL® PRFM is a regenerative aesthetic treatment that uses your body’s own platelet-rich fibrin matrix to support collagen production, improve skin quality, and create Selphyller Gel™, a natural plasma-based filler designed to restore volume and support long-term rejuvenation. Blessed Beauty Boutique offers SELPHYL® PRFM to patients in Greater Phoenix.

SELPHYL® PRFM represents a new generation of regenerative aesthetic medicine that combines natural tissue rejuvenation with volume restoration using your body’s own platelet rich fibrin matrix. By harnessing your natural healing potential, SELPHYL® helps support healthier skin while restoring a refreshed, youthful appearance. Rather than simply filling lines or replacing lost volume, this advanced treatment harnesses your body’s own healing potential to support healthier, smoother, and more youthful looking skin. You may have looked in the mirror and felt like your reflection no longer matches how energetic and confident you feel inside. Perhaps you have noticed thinning skin, loss of facial volume, or a tired appearance but worry that traditional fillers may look unnatural. Many people want visible improvement without looking like they have had cosmetic work done. Modern aesthetic medicine is shifting away from simply masking the signs of aging and toward supporting the body’s natural ability to repair, regenerate, and restore healthier tissue over time. Research continues to demonstrate the value of platelet-based regenerative therapies for supporting collagen production, improving skin quality, and encouraging natural tissue renewal that contributes to both immediate and long-term aesthetic improvements. Blessed Beauty Boutique combines regenerative aesthetic expertise with advanced SELPHYL® PRFM techniques to help patients improve skin quality, stimulate collagen production, and restore facial volume using their body’s own natural healing resources.

Unlike treatments that focus only on correcting visible concerns, regenerative aesthetic care works to support the biological processes that contribute to healthier, more resilient skin. Together, you can explore a treatment plan that aligns with your goals, respects your natural appearance, and supports lasting confidence. Serving Phoenix, Arizona and surrounding Phoenix–Mesa–Chandler communities, Blessed Beauty Boutique helps patients achieve natural looking facial rejuvenation through advanced regenerative aesthetic treatments that work with the body’s own healing processes.

What could change in your confidence if your skin looked healthier, more vibrant, and naturally refreshed without sacrificing the features that make you uniquely you? Call Blessed Beauty Boutique at (480) 935-7478 to learn whether SELPHYL® PRFM may be the right regenerative treatment for your aesthetic goals.

Why Patients are Choosing SELPHYL^® PRFM

Uses Body’s Own Healing Properties

SELPHYL® PRFM helps restore a refreshed and youthful appearance without changing the features that make you unique. Instead of creating an artificial or overfilled look, it works with your body’s natural regenerative processes to help you look rested, vibrant, and confident.

Improves Skin Texture and Quality

Collagen is one of the key building blocks of healthy, youthful skin, yet production naturally declines with age. SELPHYL® PRFM delivers concentrated growth factors that help stimulate collagen formation, supporting firmer skin, improved elasticity, and smoother texture over time.

Natural Alternative to Synthetic Fillers

Because SELPHYL® PRFM is created from your own platelet-rich fibrin matrix, the treatment harnesses your body’s natural ability to repair and rejuvenate tissue. This regenerative approach offers a highly personalized treatment designed to work in harmony with your biology.

Supports Healthier Skin Quality

Healthy skin is about more than reducing wrinkles. SELPHYL® PRFM helps support smoother texture, improved tone, enhanced radiance, and stronger skin quality, creating a healthier appearance that reflects how you feel on the inside.

Supports Collagen Production

Selphyller Gel™ is created from your own platelet-rich fibrin matrix and serves as a natural plasma-based filler that supports facial contours while encouraging ongoing tissue regeneration. This allows many patients to achieve subtle volume restoration without relying exclusively on synthetic filler products.

Rejuvenation & Volume in One Treatment

Most aesthetic treatments focus on either restoring volume or improving skin quality. SELPHYL® PRFM with Selphyller Gel™ helps address both by supporting collagen production, tissue regeneration, and natural volume restoration within a single regenerative treatment approach.

SELPHYL® PRFM

Concerns Addressed

FAQs

SELPHYL® PRFM

Concerns Addressed

FAQs

Ready To Invest In Healthier,
More Youthful Looking Skin?

Blessed Beauty Boutique will create a personalized regenerative aesthetic treatment plan designed to support natural rejuvenation and long-term skin health.

Call Blessed Beauty Boutique at (480) 935-7478 to schedule your personalized SELPHYL® PRFM consultation and discover how regenerative aesthetics can help you achieve natural looking facial rejuvenation.

Advanced AntiAging
Aesthetic Treatments

At Blessed Beauty Boutique, aesthetics is never about overdoing; it’s about honoring your features with precision, care, and artistry. Led by Isabella Leviyev, PA-C, our boutique practice delivers natural-looking results using advanced injectables, PRF, laser therapy, PDO threads, and medical-grade skincare. With over 17 years of clinical expertise and an eye for subtle beauty, Isabella designs every treatment to enhance, not erase, what makes you uniquely you.

Whether you’re new to aesthetics or refining your routine, our treatments are always safe, evidence-based, and emotionally attuned. Patients feel empowered, informed, and radiant; not just after their visit, but every time they look in the mirror. You deserve results that feel like you, just more refreshed, balanced, and confident.

Client Reviews

    
 
 
       Posted on Google  
   
   Todd Schwartz 
 
 
 
 Trustindex verifies that the original source of the review is Google. Very unique approach to my health and I love it! Dr. Isabella is using a dry needle approach to my lower back and jaw pain, as well as trying to help me sleep. So many services she offers, her staff is wonderful, so glad I found them and I called them initially for testosterone therapy, but were working on all my issues..
  
 
      Posted on Google  
   
   Roberta Levi 
 
 
 
 Trustindex verifies that the original source of the review is Google. I was waiting for this appointment for so long. The place is beautiful and so pleasant. Everyone is so friendly and Charley is a true professional and made me feel so good. This is a fantastic location with enough parking which adds to the experience. Thank you Blessed Beauty Boutique for an amazing experience!
  
 
      Posted on Google  
   
   Angel Angel 
 
 
 
 Trustindex verifies that the original source of the review is Google. Congratulation for Blessed Beauty Boutique New location,it's very beautiful!!! Dr.Isabellavery professional and make you feel comfortable trough every service. Dr.Isabella hears all your thoughts and wishes to perfection. I highly recommend Blessed Beauty Boutique place.
  
 
      Posted on Google  
   
   Denise Gullickson 
 
 
 
 Trustindex verifies that the original source of the review is Google. I have been going to Isabella for several years now! She does her research and is very knowledgeable on her services. I love the Radiesse injectable that stimulates my own collagen! I am older and it makes my face look fuller but natural! I trust her knowledge and ethics!💕
  
 
      Posted on Google  
   
   Judy cox 
 
 
 
 Trustindex verifies that the original source of the review is Google. Friendly staff and beautiful atmosphere. I have used skin tightening sessions and love the new zerf machine. They do good work there.
  
 
      Posted on Google  
   
   zisha gelfand 
 
 
 
 Trustindex verifies that the original source of the review is Google. I am so grateful to have found Dr. Leviev, she truly listens to me and takes the time to understand my concerns,she is open minded and willing to work with me
  
 
      Posted on Google  
   
   Debra Stamm 
 
 
 
 Trustindex verifies that the original source of the review is Google. My experience since day one with Blessed Beauty has been amazing. Isabella is fantastic. The whole team gets five stars for me.
  
 
      Posted on Google  
   
   Lexi Dominguez 
 
 
 
 Trustindex verifies that the original source of the review is Google. I had a great experience with Blessed Beauty Boutique. Isabella was knowledgeable, professional, and always the time to explain everything clearly and answer any concerns I have. She is very knowledgeable and I never leave with any questions!
  
 
      Posted on Google  
   
   Christine Smith 
 
 
 
 Trustindex verifies that the original source of the review is Google. It was a great experience of finding out more about me and we treated the reason for coming in but still discussed some other possibilities for treatment, which was amazing!
  
 
      Posted on Google  
   
   Kelly Novak 
 
 
 
 Trustindex verifies that the original source of the review is Google. The girls at BBB are amazing.

SELPHYL^®
PRFM

Why Patients are Choosing SELPHYL^® PRFM

Uses Body’s Own Healing Properties

Improves Skin Texture and Quality

Natural Alternative to Synthetic Fillers

Supports Healthier Skin Quality

Supports Collagen Production

Rejuvenation & Volume in One Treatment

Natural Rejuvenation Meets Regenerative Volume Restoration

Why Your Skin Changes Over Time

Collagen Breakdown

Facial Volume Loss

Slower Tissue Regeneration

Skin Texture and Elasticity Changes

Frequently Asked Questions

Ready To Invest In Healthier,
More Youthful Looking Skin?

Advanced AntiAging
Aesthetic Treatments

Client Reviews

Address

Phone

SELPHYL®PRFM

Why Patients are Choosing SELPHYL® PRFM

Uses Body’s Own Healing Properties

Improves Skin Texture and Quality

Natural Alternative to Synthetic Fillers

Supports Healthier Skin Quality

Supports Collagen Production

Rejuvenation & Volume in One Treatment

Natural Rejuvenation Meets Regenerative Volume Restoration

Why Your Skin Changes Over Time

Collagen Breakdown

Facial Volume Loss

Slower Tissue Regeneration

Skin Texture and Elasticity Changes

Frequently Asked Questions

Ready To Invest In Healthier,More Youthful Looking Skin?

Advanced AntiAgingAesthetic Treatments

Client Reviews

SELPHYL^®
PRFM

Why Patients are Choosing SELPHYL^® PRFM

Ready To Invest In Healthier,
More Youthful Looking Skin?

Advanced AntiAging
Aesthetic Treatments